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When side effects do occur, they are often minor and either require no treatment or can easily be treated by your healthcare provider.
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The only question that matters is if you have purchased a license with an available guest virtualization right for 2012R2. While not serious, it is one that is not likely to subside. I have only been on the drug for three days (200mg, 3 times a day) and have not noticed any bad side effects and have had some reduction in pain.
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